Patient Type | Intensive Care Unit | non-Intensive Care Unit |
---|---|---|
CVC or Midline Catheter Present | Topical chlorhexidine gluconate (at least 2%) + Intranasal antistaphyloccal antibiotic/antiseptic (e.g. mupirocin or iodophor) (core strategy) | Topical chlorhexidine gluconate (at least 2%) + Intranasal antistaphyloccal antibiotic/antiseptic (e.g. mupirocin or iodophor) (supplemental strategy) |
No CVC or Midline Catheter present | Topical chlorhexidine gluconate (at least 2%) + Intranasal antistaphyloccal antibiotic/antiseptic (i.e. mupirocin or iodophor) (core strategy) | None (note that source control strategies may apply to pre-operative surgical patients outside the intensive care unit- see section 1on SSI prevention) |
References
- O’Grady NP, Alexander M, Burns LA, Dellinger EP, Garland J and the Healthcare Infection Control Practices Advisory Committee (HICPAC). Guidelines for the Prevention of Intravascular Catheter-Related Infections, 2011[PDF – 83 pages].
- Marschall J, Mermel LA, Fakih M, Hadaway L, Kallen A, et al. Strategies to Prevent Central Line–Associated Bloodstream Infections in Acute Care Hospitals: 2014 Update by the Infectious Disease Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA). Infection Control and Hospital Epidemiology, Volume 35 (S2), July 2014, S89-S107.
- Berrios-Torres SI, Umscheid CA, Bratzler DW, Leas B, Stone EC, et al. Centers for Disease Control and Prevention Guidelines for the Prevention of Surgical Site Infection, 2017. JAMA Surgery, special web publication, May 2017.
- Anderson DJ, Podgorny K, Berrios-Torres SI, Bratzler DW, Dellinger EP, et al. Strategies to Prevent Surgical Site Infections in Acute Care Hospitals: 2014 Update by the Infectious Disease Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA). Infection Control and Hospital Epidemiology, Volume 35 (S2), June 2014, S66-S88.
- Bode LG, Kluytmans JA, Wertheim HF, Bogaers D, Vandenbroucke-Grauls CM, et al. Preventing Surgical-Site Infections in Nasal Carriers of Staphylococcus aureus. New England Journal of Medicine, Volume 362 (1), January 2010, 9-17.
- Perl TM, Cullen JJ, Wenzel RP, Zimmermean MB, Pfaller MA, et al. Intranasal Mupirocin to Prevent Postoperative Staphylococcus aureus Infections. New England Journal of Medicine, Volume 346 (24), June 2002, 1871-1877.
- Schweizer ML, Chang HY, Septimus E, Moody J, Braun B, et al. Association of a Bundled Intervention With Surgical Site Infections Among Patients Undergoing Cardiac, Hip, or Knee Surgery. JAMA, Volume 313 (21), June 2015, 2162-2171.
- Klompas M, Branson R, Eichenwald EC, Greene LR, Howell MD, et al. Strategies to Prevent Ventilator-Associated Pneumonia in Acute Care Hospitals: 2014 Update by the Infectious Disease Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA). Infection Control and Hospital Epidemiology, Volume 35 (8), August 2014, 915-936.
- Huang SS, Septimus E, Kleinman K, Moody J, Hickok J, et al. Targeted Versus Universal Decolonization to Prevent ICU Infection. NEJM, Volume 368 (24), June 2014, 2255-2265.
- Huang SS, Septimus E, Kleinman K, Moody J, Hickok J, et al. Chlorhexidine versus Routine Bathing to Prevent Multi Drug-Resistant Organisms and All-Cause Bloodstream Infection in General Medical and Surgical Units: The ABATE Infection Cluster Randomized Trial. Lancet, in press.
- Universal ICU Decolonization: An Enhanced Protocol. Agency for Healthcare Research and Quality (AHRQ).
- Core Infection Prevention and Control Practices for Safe Healthcare Delivery in All Settings – Recommendations of the Healthcare Infection Control Practices Advisory Committee. 2017.[PDF – 15 pages].
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