Wednesday, March 27, 2019

Medical News | Medical Articles | Antibodies - Mar 27, 2019 Edition

Medical News | Medical Articles

 
 March 27, 2019 
 Antibodies 
 The latest antibodies news from News Medical 
 #ALT#SEC-MALS for absolute biophysical characterization

Molar mass, aggregates, fragments and complexes: SEC-MALS is essential. Characterize the solution properties of biomolecules without reference to standards, conformation or column elution properties.

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  KeysightMonitoring Cancer Treatments with Immuno-PETThe clinical use of full-length mAbs as imaging agents can be challenging, due to their long biological half-life and relatively slow tumor penetration, which may affect tumor-to-background contrast at early time points. In this webinar, Dr Gabriela Kramer-Marek will focus on HER-specific imaging radioconjugates that could provide unique information as cancer biomarkers, including quantification of receptor heterogeneity and early detection of changes in target expression in response to therapy.

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   IgG antibodies play unexpected role in atherosclerosisIgG antibodies play unexpected role in atherosclerosis
 
Researchers at Karolinska Institutet in Sweden have found that type IgG antibodies play an unexpected role in atherosclerosis. A study on mice shows that the antibodies stabilize the plaque that accumulates on the artery walls, which reduces the risk of it rupturing and causing a blood clot. It is hoped that the results, which are published in the journal Circulation, will eventually lead to improved therapies.
 
 Role of immunological imprinting in elicitation of new antibodies
 
Role of immunological imprinting in elicitation of new antibodiesWe are repeatedly exposed to the influenza virus via infections, vaccinations and our communal environments. The annual flu shot is believed to be the best line of defense, and doctors recommend vaccinations every year because the flu virus is in a constant state of adaptation and mutation, rendering older vaccines obsolete.
 
 
 Premature babies also have protective anti-viral antibodies
 
Premature babies also have protective anti-viral antibodiesEven premature babies carry anti-viral antibodies transferred from the mother, researchers at Karolinska Institutet in Sweden report in a paper on maternal antibodies in newborns, published in the journal Nature Medicine.
 
 
 Blood donors' leftover immune cells provide crucial insights into antibody affinity
 
Blood donors' leftover immune cells provide crucial insights into antibody affinityDuring some kinds of blood donations, you get most of your blood back. For example, platelet donation involves a procedure in which donor blood is filtered to harvest the platelets for medical use and the rest of the blood components are returned to the donor's body.
 
 
 Custom-made proteins could result in antibodies that fight HIV
 
Custom-made proteins could result in antibodies that fight HIVResearchers have developed a new method for the creation of custom-made proteins that can bypass the protective coating of the HIV virus, allowing antibodies to neutralize the Env gene, which enables the virus to bind and enter human immune cells.
 
 
 Researchers define pathway that helps us make antibodies
 
Researchers define pathway that helps us make antibodiesOur bodies are continuously concocting specific antibodies to thwart invaders like a virus or even pollen, and scientists have new information about how the essential production gets fired up and keeps up.
 

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