Genomics & Health Impact Scan Database|Search|PHGKB

Genomics & Health Impact Scan Database|Search|PHGKB

Genomics and Precision Health Database

Publication
BRCA1 and BRCA2 Gene Mutations and Colorectal Cancer Risk: Systematic Review and Meta-analysis. Oh Mok et al. Journal of the National Cancer Institute 2018 110(11) 1178-1189 Similar articles in PubMed
A Cost-effectiveness Analysis of Multigene Testing for All Patients With Breast Cancer L Sun et al, JAMA Oncology, October 3, 2019
A Value of Information Analysis of Research on the 21-Gene Assay for Breast Cancer Management. Kunst Natalia R et al. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 2019 Oct 22(10) 1102-1110 Similar articles in PubMed
The Impact of Biomarker Screening and Cascade Genetic Testing on the Cost-Effectiveness of MODY Genetic Testing. GoodSmith Matthew S et al. Diabetes care 2019 Sep Similar articles in PubMed
Cost-effectiveness Analysis of CYP2D6*10 Pharmacogenetic Testing to Guide the Adjuvant Endocrine Therapy for Postmenopausal Women with Estrogen Receptor Positive Early Breast Cancer in China. Wei Xiaoxia et al. Clinical drug investigation 2019 Sep Similar articles in PubMed
Prevalence of Immunodeficiency in Children With Invasive Pneumococcal Disease in the Pneumococcal Vaccine Era: A Systematic Review. Butters Coen et al. JAMA pediatrics 2019 Sep Similar articles in PubMed
A Rapid Systematic Review of Outcomes Studies in Genetic Counseling. Madlensky Lisa et al. Journal of genetic counseling 2017 Jun 26(3) 361-378 Similar articles in PubMed
Stakeholders' perspectives on the post-mortem use of genetic and health-related data for research: a systematic review. Bak Marieke A R et al. European journal of human genetics : EJHG 2019 Sep Similar articles in PubMed
Estimating the fiscal impact of rare diseases using a public economic framework: a case study applied to hereditary transthyretin-mediated (hATTR) amyloidosis. Connolly Mark P et al. Orphanet journal of rare diseases 2019 Sep 14(1) 220 Similar articles in PubMed
Supervision in genetic counselor training in North America: A systematic review. Siskind Carly E et al. Journal of genetic counseling 2019 Sep Similar articles in PubMed
Circulating miRNAs as Novel Diagnostic Biomarkers in Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis. Cai Changzhou et al. Canadian journal of gastroenterology & hepatology 2019 20192096161 Similar articles in PubMed
Detection of RAS mutations in circulating tumor DNA: a new weapon in an old war against colorectal cancer. A systematic review of literature and meta-analysis. Galvano Antonio et al. Therapeutic advances in medical oncology 2019 111758835919874653 Similar articles in PubMed
The Influence of Beta-2 Adrenergic Receptor Gene Polymorphisms on Albuterol Therapy for Patients With Asthma: Protocol for a Systematic Review and Meta-Analysis. Hikino Keiko et al. JMIR research protocols 2019 Sep 8(9) e14759 Similar articles in PubMed
Cost effectiveness of bilateral risk-reducing mastectomy and salpingo-oophorectomy. Schrauder Michael G et al. European journal of medical research 2019 Sep 24(1) 32 Similar articles in PubMed
Can preimplantation genetic diagnosis be used for monogenic endocrine diseases? Yeager Stephanie et al. Journal of pediatric endocrinology & metabolism : JPEM 2019 Sep Similar articles in PubMed
Regional models of genetic services in the United States. Kaye Celia et al. Genetics in medicine : official journal of the American College of Medical Genetics 2019 Sep Similar articles in PubMed
Lethal privacy: Quantifying life years lost if the right to informational self-determination guides genetic screening for Lynch syndrome. Gansen Fabia et al. Health policy (Amsterdam, Netherlands) 2019 Aug Similar articles in PubMed
Polymorphisms of genes encoding drug transporters or cytochrome P450 enzymes and association with clinical response in cancer patients: a systematic review. Kulma Inthuorn et al. Cancer chemotherapy and pharmacology 2019 Sep Similar articles in PubMed
Estimating the Prevalence of Familial Hypercholesterolemia in Acute Coronary Syndrome: A Systematic Review and Meta-analysis. Kramer Adam I et al. The Canadian journal of cardiology 2019 Jun Similar articles in PubMed
Reporting of race in genome and exome sequencing studies of cancer: a scoping review of the literature. Nugent Adrienne et al. Genetics in medicine : official journal of the American College of Medical Genetics 2019 Jun Similar articles in PubMed
Are There Different Evidence Thresholds for Genomic Versus Clinical Precision Medicine? A Value of Information-Based Framework Applied to Antiplatelet Drug Therapy. Guzauskas Gregory F et al. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 2019 Sep 22(9) 988-994 Similar articles in PubMed
Effectiveness of a Pharmacogenetic Tool at Improving Treatment Efficacy in Major Depressive Disorder: A Meta-Analysis of Three Clinical Studies. Vilches Silvia et al. Pharmaceutics 2019 Sep 11(9) Similar articles in PubMed
Endocrine treatment versus chemotherapy in postmenopausal women with hormone receptor-positive, HER2-negative, metastatic breast cancer: a systematic review and network meta-analysis. Giuliano Mario et al. The Lancet. Oncology 2019 Sep Similar articles in PubMed
From Paper to Digital Applications of the Pain Drawing: Systematic Review of Methodological Milestones. Shaballout Nour et al. JMIR mHealth and uHealth 2019 Sep 7(9) e14569 Similar articles in PubMed
Clinical Decision-Support Systems for Detection of Systemic Inflammatory Response Syndrome, Sepsis, and Septic Shock in Critically Ill Patients: A Systematic Review. Wulff Antje et al. Methods of information in medicine 2019 Sep Similar articles in PubMed
Cost-effectiveness analysis of reflex testing for Lynch syndrome in women with endometrial cancer in the UK setting. Snowsill Tristan M et al. PloS one 2019 14(8) e0221419 Similar articles in PubMed
Reinforcement learning in clinical medicine: a method to optimize dynamic treatment regime over time. Zhang Zhongheng et al. Annals of translational medicine 2019 Jul 7(14) 345 Similar articles in PubMed
A Decision-Theoretic Approach to Panel-Based, Preemptive Genotyping. Shi Yaping et al. MDM policy & practice 4(2) 2381468319864337 Similar articles in PubMed
Social network interventions for health behaviours and outcomes: A systematic review and meta-analysis. Hunter Ruth F et al. PLoS medicine 2019 Sep 16(9) e1002890 Similar articles in PubMed
Prenatal genetic testing for cystic fibrosis: a systematic review of clinical effectiveness and an ethics review. Kessels Sharon J M et al. Genetics in medicine : official journal of the American College of Medical Genetics 2019 Aug Similar articles in PubMed
Diagnostic significance assessment of the circulating cell-free DNA in ovarian cancer: An updated meta-analysis. Li Boxuan et al. Gene 2019 Sep 714143993 Similar articles in PubMed
No. 365-Fetal and Perinatal Autopsy in Prenatally Diagnosed Fetal Abnormalities with Normal Chromosome Analysis. Fallet-Bianco Catherine et al. Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC 2018 Oct 40(10) 1358-1366.e5 Similar articles in PubMed
Application of Economic Evaluation to Assess Feasibility for Reimbursement of Genomic Testing as Part of Personalized Medicine Interventions. Simeonidis Stavros et al. Frontiers in pharmacology 2019 10830 Similar articles in PubMed
Quantitative risk of positive family history in developing colorectal cancer: A meta-analysis. Mehraban Far Parsa et al. World journal of gastroenterology 2019 Aug 25(30) 4278-4291 Similar articles in PubMed
Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer in Women: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. Nelson Heidi D et al. JAMA 2019 322(7) 666-685 Similar articles in PubMed
Deep Learning and Neurology: A Systematic Review. Valliani Aly Al-Amyn et al. Neurology and therapy 2019 Aug Similar articles in PubMed
Use of machine learning to analyse routinely collected intensive care unit data: a systematic review. Shillan Duncan et al. Critical care (London, England) 2019 Aug 23(1) 284 Similar articles in PubMed
The utility of Ki-67 as a prognostic biomarker in pulmonary neuroendocrine tumours: protocol for a systematic review and meta-analysis. Naheed Salma et al. BMJ open 2019 Aug 9(8) e031531 Similar articles in PubMed
DeepCC: a novel deep learning-based framework for cancer molecular subtype classification. Gao Feng et al. Oncogenesis 2019 Aug 8(9) 44 Similar articles in PubMed
Molecular Testing Versus Diagnostic Lobectomy in Bethesda III/IV Thyroid Nodules: A Cost-Effectiveness Analysis. Nicholson Kristina et al. Thyroid : official journal of the American Thyroid Association 2019 Aug Similar articles in PubMed
Cost-utility analysis of genetic polymorphism universal screening in colorectal cancer prevention by detection of high-risk individuals. Pereira Carina et al. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2019 Aug Similar articles in PubMed
Breast cancer risk assessment: Evaluation of screening tools for genetics referral. Himes Deborah O et al. Journal of the American Association of Nurse Practitioners 2019 Aug Similar articles in PubMed
Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer in Women Updated Evidence Report and Systematic Review for the US Preventive Services Task Force HD Nelson et al, JAMA, August 20, 2019
The Prognostic Value of the MiR-200 Family in Colorectal Cancer: A Meta-analysis with 1882 Patients. Yu Chengpeng et al. Journal of Cancer 2019 10(17) 4009-4016 Similar articles in PubMed
Risk of Ischemic Stroke and Peripheral Arterial Disease in Heterozygous Familial Hypercholesterolemia: A Meta-Analysis. Akioyamen Leo E et al. Angiology 2019 Sep 70(8) 726-736 Similar articles in PubMed
Research on Artificial Intelligence and Primary Care: A Scoping Review J Kueper et al, MexRXIV, AUgust 21, 2019
Automated Segmentation of Tissues Using CT and MRI: A Systematic Review. Lenchik Leon et al. Academic radiology 2019 Aug Similar articles in PubMed
Artificial Intelligence Versus Clinicians in Disease Diagnosis: Systematic Review. Shen Jiayi et al. JMIR medical informatics 2019 Aug 7(3) e10010 Similar articles in PubMed
Machine learning applications to clinical decision support in neurosurgery: an artificial intelligence augmented systematic review. Buchlak Quinlan D et al. Neurosurgical review 2019 Aug Similar articles in PubMed
Diagnostic DNA Methylation Biomarkers for Renal Cell Carcinoma: A Systematic Review. Lommen Kim et al. European urology oncology 2019 Aug Similar articles in PubMed
Benefits, harms and cost-effectiveness of cancer screening in Australia: an overview of modelling estimates. Lew Jie-Bin et al. Public health research & practice 2019 Jul 29(2) Similar articles in PubMed
The use and performance of artificial intelligence applications in dental and maxillofacial radiology: A systematic review. Hung Kuofeng et al. Dento maxillo facial radiology 2019 Aug 20190107 Similar articles in PubMed
Cost-Effectiveness Analysis of a HMGA2 Prognostic Test for Acute Myeloid Leukemia in a Canadian Setting. Tremblay Gabriel et al. Applied health economics and health policy 2019 Aug Similar articles in PubMed
Identification of microRNA biomarkers in atrial fibrillation: A protocol for systematic review and bioinformatics analysis. Shen Nan-Nan et al. Medicine 2019 Jul 98(30) e16538 Similar articles in PubMed
Enablers and barriers to treatment adherence in heterozygous familial hypercholesterolaemia: a qualitative evidence synthesis. Kinnear Fiona J et al. BMJ open 2019 Jul 9(7) e030290 Similar articles in PubMed
A 23 gene-based molecular prognostic score precisely predicts overall survival of breast cancer patients. Shimizu Hideyuki et al. EBioMedicine 2019 Jul Similar articles in PubMed
MicroRNAs as biomarkers of harmful environmental and occupational exposures: a systematic review. Kotsyfakis Michail et al. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2019 Aug 1-20 Similar articles in PubMed
Effectiveness of decision aids for female BRCA1 and BRCA2 mutation carriers: a systematic review. Krassuski Lisa et al. BMC medical informatics and decision making 2019 Aug 19(1) 154 Similar articles in PubMed
Screening for Pancreatic Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. Henrikson Nora B et al. JAMA 2019 Aug 322(5) 445-454 Similar articles in PubMed
Internet-based interventions for adults with hearing loss, tinnitus and vestibular disorders: a protocol for a systematic review. Beukes Eldr? W et al. Systematic reviews 2018 7(1) 205 Similar articles in PubMed
CLINGEN Actionability Report for Familial Adenomatous Polyposis - APC ClinGen Actionability Working Group
CLINGEN Actionability Report for Marfan Syndrome - FBN1 ClinGen Actionability Working Group
CLINGEN Actionability Report for Factor V Leiden, Homozygous (also includes compound heterozygous FVL + prothrombin G20210A) - F5 ClinGen Actionability Working Group
CLINGEN Actionability Report for Hereditary Hemorrhagic Telangiectasia - ENG, ACVRL1, SMAD4, GDF2 ClinGen Actionability Working Group
CLINGEN Actionability Report for Phenylketonuria (PKU) - PAH ClinGen Actionability Working Group
CLINGEN Actionability Report for Malignant Hyperthermia Susceptibility - RYR1, CACNA1S ClinGen Actionability Working Group
CLINGEN Actionability Report for MUTYH-Associated Polyposis - MUTYH ClinGen Actionability Working Group
CLINGEN Actionability Report for Dilated cardiomyopathy - DMD, LMNA, TNNT2 ClinGen Actionability Working Group
CLINGEN Actionability Report for von Willebrand Disease - VWF ClinGen Actionability Working Group
CLINGEN Actionability Report for Von Hippel-Lindau Syndrome - VHL ClinGen Actionability Working Group
CLINGEN Actionability Report for POLE and POLD1 associated susceptibility to C- POLE, POLD1 ClinGen Actionability Working Group
CLINGEN Actionability Report for Factor XI Deficiency - F11 ClinGen Actionability Working Group
CLINGEN Actionability Report for Hereditary mixed polyposis syndrome 1- GREM1 ClinGen Actionability Working Group
CLINGEN Actionability Report for Breast Cancer - ATM, CHEK2 ClinGen Actionability Working Group
CLINGEN Actionability Report for Acute Intermittent Porphyria - HMBS ClinGen Actionability Working Group
CLINGEN Actionability Report for Familial papillary renal cell carcinoma 1 - MET ClinGen Actionability Working Group
CLINGEN Actionability Report for Glutaric Acidemia I - GCDH ClinGen Actionability Working Group
CLINGEN Actionability Report for Fabry Disease - GLA ClinGen Actionability Working Group
CLINGEN Actionability Report for Peutz-Jeghers Syndrome - STK11 ClinGen Actionability Working Group
CLINGEN Actionability Report for Adrenoleukodystrophy - ABCD1 ClinGen Actionability Working Group
CLINGEN Actionability Report for Ehlers-Danlos Syndrome Type IV - COL3A1 ClinGen Actionability Working Group
CLINGEN Actionability Report for Basal Cell Nevus Syndrome (BCNS) - PTCH1 ClinGen Actionability Working Group
CLINGEN Actionability Report for Multiple Endocrine Neoplasia Type IIB - RET ClinGen Actionability Working Group
CLINGEN Actionability Report for Multiple Endocrine Neoplasia Type I - MEN1 ClinGen Actionability Working Group
CLINGEN Actionability Report for Hypophosphatemic rickets, autosomal dominant-FGF23 ClinGen Actionability Working Group
CLINGEN Actionability Report for Acrodermatitis enteropathica, zinc-deficiency type-SLC39A4 ClinGen Actionability Working Group
CLINGEN Actionability Report for Homocystinuria due to Cystathionine Beta-Synthase Deficiency - CBS ClinGen Actionability Working Group
CLINGEN Actionability Report for Alpha-1 Antitrypsin Deficiency - SERPINA1 ClinGen Actionability Working Group
CLINGEN Actionability Report for Charcot - Marie - Tooth Disease, Type 1 - PMP22, MPZ, LITAF, EGR2, NEFL ClinGen Actionability Working Group
CLINGEN Actionability Report for Glycogen Storage Disease 2 - GAA ClinGen Actionability Working Group
CLINGEN Actionability Report for Romano-Ward Long QT Syndrome - KCNQ1, KCNH2, SCN5A ClinGen Actionability Working Group
CLINGEN Actionability Report for Hereditary Breast and Ovarian Cancer- BRCA1, BRCA2 ClinGen Actionability Working Group
CLINGEN Actionability Report for Ovarian cancer - RAD51C, RAD51D, BRIP1 ClinGen Actionability Working Group
CLINGEN Actionability Report for Thrombophilia due to protein S deficiency - PROS1 ClinGen Actionability Working Group
CLINGEN Actionability Report for Tumor Predisposition Syndrome - BAP1 ClinGen Actionability Working Group
CLINGEN Actionability Report for F5: Factor V deficiency (AR) - F5 ClinGen Actionability Working Group
CLINGEN Actionability Report for WAS-related disorders-WAS ClinGen Actionability Working Group
CLINGEN Actionability Report for Wilms tumor-WT1 ClinGen Actionability Working Group
CLINGEN Actionability Report for Ehlers-Danlos syndrome, classic type - COL5A1, COL5A2 ClinGen Actionability Working Group
CLINGEN Actionability Report for Pancreatic cancer/melanoma syndrome - CDKN2A ClinGen Actionability Working Group