Themesothelioma News: Medical News | Medical Articles: Spatial Gene Expression Profiling of Neurological Disorders

Tuesday, October 15, 2019

Medical News | Medical Articles: Spatial Gene Expression Profiling of Neurological Disorders

	October 15, 2019
	Genomics
	The latest genomics news from News-Medical

Spatial Gene Expression Profiling of Neurological Disorders

Unraveling the complexities of the nervous system requires both an understanding of what is happening and where. In this interview, Cedric Uytingco describes the key benefits of being able to visualize gene expression patterns in neurological samples.

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Tips, Tricks and Solutions for Effective Sample Management

Sample management is the selecting, collecting, storage, and retrieval of samples and their inherent data. It is a fundamental part of quality control in a laboratory and, if overlooked, can have costly and time-consuming repercussions. An informative and unbiased guide addresses key topics including:

What is sample management?
Top tips for tube selection and labelling
Top tips for sample collection
The importance of an effective sample management system cannot be overstated.

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Genetic mutation appears to help people fight off MRSA

Researchers at Duke University have discovered that people who carry a certain genetic mutation may have a greater chance of fighting off methicillin-resistant Staphylococcus aureus (MRSA) infections.

	Researchers uncover fundamental difference in how DNA is held together esearchers at Chalmers University of Technology in Sweden have made an important discovery about DNA that could completely change how scientists understand medicine and the life sciences. As reported in the journal PNAS, Bobo Feng and colleagues have disproved what had been the prevailing theory about how DNA holds itself together.

	Study uncovers epigenetic origins for hypersexual disorder Overactivity of the hormone oxytocin has been identified as a potential key element in hypersexual disorder, a compulsive sexual disorder that affects around 3 to 6 percent of the population. The discovery could lead to pharmacological treatments that target oxytocin activity.

	Developing a highly predictive genetic risk score for type 1 diabetes Paul Tran is working to develop a highly predictive genetic risk score that will tell parents whether their baby is at significant risk for type 1 diabetes. The ultimate goal, says the MD/PhD student at the Medical College of Georgia at Augusta University, is to prevent a condition that typically surfaces in youth, destroys the pancreas, and leads to a lifetime of insulin therapy or a pancreas transplant.

	Novel viral vector improves gene therapy for sickle cell disease Researchers at the National Institutes of Health (NIH) have developed a unique, improved viral vector to use in gene therapy for sickle cell disease. Using animal models, the new vector was shown to support the transfer of corrective genes into bone marrow stem cells up to ten times more efficiently than current vectors. It also had a carrying capacity that was ten times greater than conventional vectors.

	Scientists use ultrasound to detect active genes in live cells A startling new study published in the journal Science shows that ultrasound can help scientists to understand whether specific genes are in the active or inactive state in live cells. This incredible feat promises to transform the way scientists examine a host of living cell activities, ranging from the growth of tumors to neuron function.

	Reactivating ‘tumor suppressor’ genes could offer new therapeutic approach for cancer Scientists have developed a method which is able to switch ‘tumor suppressor’ genes back on after they have been silenced by cancer cells. The discovery has strong implications for the development of new therapies that could halt tumor growth through manipulating a regulatory protein that is commandeered by cancer cells.