Simple test could help diagnose glioblastoma
Scientists at the University of Sussex could be a step closer to developing the first-ever blood test to diagnose the most aggressive type of brain cancer, glioblastoma.
The team of researchers, working at Professor Georgios Giamas’ laboratory, has found novel biomarkers in the body fluids that could hint the presence of the tumor.
Biomarkers are biological molecules found in blood and other body fluids that could signal a normal or abnormal process, including the presence of a disease. Cancer biomarkers provide a signal of the presence of cancer cells, which are considered biological signatures of disease.
In the study published in the journal Nature Communications Biology, the researchers report that specific biomarkers linked to extracellular vesicles, which are tiny packages released by cells into body fluids so they can communicate with each other.
Extracellular vesicles (EVs) is a way through which tumor cells, which include cancer stem cells, self-regulate, and communicate with their stromal counterparts. This way, they maintain such high-tumoral heterogeneity.
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