Mesothelioma

Mesothelioma is a rare type of cancer that occurs in the lining of the body's internal organs, a thin layer of cells known as the mesothelium, which gives mesothelioma its name. While very thin, this layer of cells is vitally important to organ function and the health of the inner body structures. There are three recognized types of mesothelioma. Pleural mesothelioma occurs in the pleural lining of the lungs and is the most common form of the disease. Peritoneal mesothelioma occurs within the peritoneum, which lines the abdominal cavity and is the second most common form of the disease. Pericardial mesothelioma is the rarest variety of the disease and occurs in the pericardial lining of the heart. The primary cause of mesothelioma is exposure to asbestos, though other factors, such as smoking may increase the likeliness of mesothelioma in certain individuals.

How is Mesothelioma Treated?

Mesothelioma is an aggressive cancer but can be managed with chemotherapy, radiation therapy, and surgery. Currently, there is no known cure for asbestos cancer but several mesothelioma treatment regimens have proven to be successful in helping the mesothelioma patient avoid pain and discomfort caused by the disease. Several therapies have emerged in recent years that have extended survival rates of mesothelioma patients to levels previously thought to be impossible. Cancer centers have initiated hundreds of clinical trials in recent years to help mesothelioma patients find a therapy that works for them while still working towards a cure for future mesothelioma patients. Progressive therapies are now being developed through the International Mesothelioma Program under the direction of thoracic specialist Dr. David Sugarbaker.

How is Mesothelioma Diagnosed?

Malignant mesothelioma can be difficult to diagnose because symptoms of the disease often closely mimic those of less serious conditions. Mesothelioma diagnosis often require X-ray and other body scans (CT or MRI) in addition to a biopsy to conclusively diagnose mesothelioma. Nevertheless, those experiencing chronic cough, difficulty swallowing, chest pain, or breathing difficulties should alert their physician immediately. This is particularly true among those with a known asbestos-exposure history. Those with asbestos exposure history should communicate this to their physician even before mesothelioma symptoms appear so that they may be able to alert patients to warning signs of the disease. If detected early enough, patients may be eligible for aggressive mesothelioma treatment options, including surgical resection of the mesothelioma cancer and affected tissue. Oncologists and thoracic specialists will be able to assist the patient in determining the extent of the disease and the best mesothelioma treatment options for that particular patient.

Asbestos Exposure

Asbestos exposure was common among industrial workers. Among the more common jobsites were those in the shipbuilding industry, such as the Todd Shipyards or Newport News Naval Shipyard. Other jobsites include power plants, chemical manufacturing, or the metal works industry. Those with asbestos history should notify their doctor and learn of possible warning signs of mesothelioma caused by exposure. Those who have been made sick by asbestos exposure, including those with a mesothelioma, should fill out the form on this page to receive a free asbestos and mesothelioma information kit detailing top doctors, new mesothelioma treatments, and how to obtain financial compensation for mesothelioma disease.
(ww.maacenter.org)

Low-Dose Aspirin May Halt Breast Cancer

Research done in test tubes and in mice presented at a conference in Boston in the US at the weekend suggests taking low doses of aspirin on a regular basis may stop breast cancer from growing and spreading. However, cancer campaigners urge caution as the results are very early stage and have yet to be shown in patients.

The research team, from the Veterans Affairs Medical Center in Kansas City and the University of Kansas Medical Center, say tests on cancer cell lines and in mice show that aspirin not only significantly slows growth of cancer cells and shrinks tumors, but also stops tumor cells spreading to new sites.

Their study investigated the effect of aspirin on two types of cancer, including the so-called aggressive "triple-negative" breast cancer, which is immune to most treatments.

Triple-negative breast cancers are so-called because they lack receptors for estrogen, progesterone and Her2/neu.

The researchers presented their findings at the annual meeting of the American Society for Biochemistry and Molecular Biology. 

A meeting abstract of the study appears in the FASEB journal.

Aspirin's Effect on Cancer First Suggested 20 Years Ago

For over 20 years, since a study in Australia first suggested aspirin may have anti-cancer properties, researchers have been finding the headache drug may prevent and also treat all sorts of cancer. 

For example, there are reports that colon cancer survival improves with aspirin use, and thataspirin and other commonly used painkillers may also help guard against skin cancer. 

It has also has been shown to reduce the risk of squamous cell esophageal cancer andprostate cancer.

At first it was thought the effect only kicked in after ten years or so, but in 2019, three Lancetstudies of people in middle age taking low-dose aspirin suggested that the anti-cancer benefits may start after only three years.

Aspirin May Halt Cancer By Acting on Cancer Stem Cells

However, despite all this evidence, the underlying mechanism through which aspirin confers its anti-cancer benefits have been somewhat difficult to establish.

Now this latest study suggests that for breast cancer, it may be that aspirin interferes with the stem cells that are believed to fuel the growth and spread of tumors.

In a press statement, senior author Sushanta Banerjee, director of the cancer research unit and a professor at the University of Kansas Medical Center, says first-line chemotherapy does not destroy stem cells: eventually the tumor will start to grow again.

"If you don't target the stemness, it is known you will not get any effect," he adds, "It will relapse."

Banerjee and colleagues found that in the mouse model they used, cancer cells treated with aspirin formed no or only partial stem cells. 

And in lab tests, aspirin blocked the growth of two different breast cancer lines.

Aspirin Halted Triple-Negative Breast Cancer In Cell Lines

One of the cell lines the researchers used was of what is often called triple-negative breast cancer, which is a less common but much more difficult form of breast cancer to treat.

Banerjee, who is also a professor of medicine in the university's division of hematology and oncology, says he and his team are mainly interested in triple-negative breast cancer because the prognosis is very poor for patients who find themselves with this form of the disease.

The reaction from cancer campaigners has been welcoming but cautious.

According to The Independent, Eluned Hughes, of the UK charity Breakthrough Breast Cancer, urges caution over the "incredibly early stage research" which is yet to be replicated in human patients. But she says they will be watching its progress closely, "it could be promising for the future", and they hope to continue to see new options for patients.

Aspirin May Also Boost Treatments for Hormone-Positive Breast Cancers

The researchers say aspirin may also improve the effectiveness of current treatments for hormone-receptor-positive breast cancers. In their study, they found aspirin boosted the effect of tamoxifen, which is used to treat hormone-positive breast cancers.

Aspirin treats many different conditions. Banerjee says its ability to target several metabolic pathways could be why it is effective against cancer:

"Cancer is not a single-gene disease," explains Banerjee, "Multiple genes are involved."

Many people take a daily low dose of aspirin to lower their risk of a further heart attack orstroke, or if they have a high risk of either.

But taking aspirin is not without risks; for instance daily aspirin use can increase the risk of gastrointestinal bleeding.

Researchers are continuing to investigate whether the advantages outweigh the potential disadvantages.

In 2019 the National Cancer Institute invited scientists to explore how drugs like aspirin, primarily intended for other purposes, might also reduce the risk of developing cancer or extend survival for those who have it.

Banerjee says his lab will be applying for one of these grants.

LES CELLULES DU CANCER S’ALIMENTENT DE :

Un des hôpitaux les plus reconnus au monde change sa vision au sujet du cancer.’hôpital John’s Hopkins Hospital est un hôpital universitaire situé à Baltimore dans l’État du Maryland aux États-Unis.Fondé grâce à un don de John’s Hopkins, il est aujourd’hui un des hôpitaux les plus reconnus au monde et est classé pour la 17e année consécutive en première place du classement des meilleurs hôpitaux des États-Unis.

Après de nombreuses années à dire aux gens que la chimiothérapie est l’unique manière de traiter et éliminer le cancer, l’hôpital John Hopkins commence à dire aux gens qu’il y a d’autres alternativeque la chimio:

 Une manière efficace de combattre le cancer est de ne pas donner à manger aux cellules cancéreuses avec ces aliments dont elles ont besoin pour se multiplier.

LES CELLULES DU CANCER S’ALIMENTENT DE :

a. Le SUCRE est un aliment du cancer. Ne pas consommer de sucre coupe un des éléments les plus importants des cellules cancéreuses. Il
existe des substituts du sucre comme la saccharine, mais ils sont faits avec de l’ Aspartame et sont très nocifs… Un meilleur substitut du sucre est le miel de manuka ou la mélasse mais en petites quantités.

b.Le SEL contient un additif chimique afin de paraître blanc. Une meilleure alternative pour le sel est le sel de mer ou les sels végétaux.

c.Le LAIT cause dans le corps la production de mucus, spécialement dans le conduit intestinal.Les cellules cancéreuses s’alimentent de
mucus. En éliminant le lait et en lui substituant du lait de soja, les cellules du cancer n’ont rien à manger, par conséquent elles meurent.

d. Les cellules cancéreuses murissent dans un milieu ambiant acide. Un régime à base de VIANDE ROUGE est acide, il vaut mieux manger du poisson et un peu de poulet à la place de la viande de bœuf ou de porc. De plus, la viande contient des antibiotiques, hormones et parasites qui sont très nocifs, spécialement pour les personnes cancéreuses. La protéine de la viande est très difficile à digérer et requiert beaucoup d’enzymes. La viande qui ne se digère pas reste dans le corps et se putréfie ce qui entraîne la création de plus de toxines.

Mesothelioma & Asbestos Lawyers

Although U.S. regulations on asbestos and asbestos exposure began in the 1970s, more than three decades later people are coming to the conclusion they need a mesothelioma lawyer. One result of the long latency period of asbestos-related diseases like mesothelioma cancer is continued legal claims by patients who were made sick through no fault of their own. Companies and contractors for branches of the military that exposed workers to the toxic mineral are being held accountable.
As early as the 1930s, medical evidence linked asbestos exposure to lung disease and mesothelioma and other asbestos cancers, diseases that severely limit someone’s life expectancy. Although many companies that made or used asbestos knew about these health hazards, they continued to expose their workers and the public to them for several decades.
Many veterans are in need of a mesothelioma attorney because so many of them, especially Navy veterans, had a high risk of asbestos exposure in the U.S. military. All together, up to 3,000 Americans are diagnosed with an asbestos-related disease. If a doctor has diagnosed you or a loved one with an asbestos-related illness such as mesothelioma or lung cancer, you may have legal options to get help with medical bills and other related expenses..

Asbestos Exposure and Lawsuits

For almost a century, asbestos was one of the most commonly used construction, manufacturing and shipbuilding materials. It was also used in thousands of products and can still be found in houses, apartments buildings and other facilities built before the 1980s. Many members of the public and workers in a variety of jobs were exposed to asbestos.
Another reason for the high number of new cases: It can take up to 50 years after an exposure for patients to start showing symptoms of mesothelioma. That is why a construction worker, shipbuilder or plant employee exposed to asbestos in the 1960s or 1970s may only now be diagnosed with the disease. That is also why many companies were able to hide the fact they exposed employees and others to this toxic mineral.