Friday, May 24, 2019

Incidence of myeloproliferative neoplasms in Calgary, Alberta, Canada | BMC Research Notes | Full Text

Incidence of myeloproliferative neoplasms in Calgary, Alberta, Canada | BMC Research Notes | Full Text

BMC Research Notes



Incidence of myeloproliferative neoplasms in Calgary, Alberta, Canada

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BMC Research Notes201912:286
  • Received: 18 January 2019
  • Accepted: 18 May 2019
  • Published: 

Abstract

Objective

The incidence of the combined myeloproliferative neoplasms (MPNs) was determined for a major Canadian city. Retrospective cases of MPN diagnoses (essential thrombocythemia, polycythemia vera, and primary myelofibrosis) between 2011 to 2015 were retrieved from the Southern Alberta Cancer Cytogenetics Laboratory’s database at Alberta Public Laboratories.

Results

An incidence rate of 2.05 cases per 100,000 person-years (95% CI 1.73–2.41) was determined, giving an age-standardized Canadian incidence of 2.71 cases per 100,000 person years (95% CI 2.63–2.78). MPN diagnoses occurred at a wide age range of 8–93 (median 66) and an age-dependent increase in incidence. Incidence rates for the MPNs are first reported here for a Canadian population.

Keywords

  • Myeloproliferative neoplasm
  • Essential thrombocythemia
  • Polycythemia vera
  • Primary myelofibrosis
  • Cancer epidemiology
  • Hematological neoplasm

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