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About 300 million bits of DNA are missing from basic reference genome, report scientists

Overcoming Issues of Scale with High Throughput Next Generation Sequencing

For the past 17 years, most scientists around the globe have been using the nucleic acid sequence, or genome, an assembly of DNA information, from primarily a single individual as a kind of "baseline" reference and human species representation for comparing genetic variety among groups of people.

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			Wuhan coronavirus is genetically different from human SARS, MERS-CoV, study found The Wuhan coronavirus or the 2019-nCoV or novel coronavirus is a new human-infecting coronavirus genetically different from human SARS (Severe Acute Respiratory Syndrome), and MERS-CoV (Middle East Respiratory Syndrome), a team of scientists has found.

			New genetic screen for Huntington’s disease Huntington’s disease is a genetic disease that is debilitating and progressive leading to severe brain damage and eventual death. In patients with this autosomal dominant disease, there is presence of a protein called the Huntingtin protein that forms clumps within the brain leading to the symptoms of the disease.

	Mysterious virus found in Brazil puzzles scientists with its unique genetic makeup A team of Brazilian scientists discovered a puzzling new virus made of genetic material never seen before. But the virus won’t pose a serious health threat to humanity since it seems to only hunt amoebas.

	Researchers create new brain cancer model using genetically engineered pluripotent stem cells Using genetically engineered human pluripotent stem cells, researchers created a new type of cancer model to study in vivo how glioblastoma, the most common and aggressive form of brain cancer, develops and changes over time.

	Single-cell DNA assessment method can detect fetal genetic abnormalities Non-invasive prenatal tests are used for fetal genetic disease screening in pregnant women. In contrast, invasive tests like amniocentesis carry the risk of causing fetal harm.

	Scientists describe genetic program behind primordial lung progenitors For the first time, researchers describe the genetic program behind primordial lung progenitors--embryonic cells that give rise to all the cells that form the lining of the respiratory system after birth.

	Developing tests for genetic signs could lead to earlier cancer detection Early signs of cancer can appear years before diagnosis and developing tests for these genetic signs could provide new ways to spot cancer early.